1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
ELEN [110]
3 years ago
15

Sickle cell anemia is caused by a single point mutation, in one of the exons that codes for the synthesis of β-globin. The pictu

re below shows the DdeI restriction sites in the normal and sickle cell alleles of the β-globin gene. Notice that the mutation that causes sickle cell eliminates the second DdeI site. On the gel provide below draw what the restriction fragments would look like for an individual that is homozygous for the normal allele (AA), for an individual that is a heterozygous carrier (AS), and for an individual with sickle cell disease (SS). How many bands would appear on the gel of the heterozygote?

Biology
1 answer:
Alenkasestr [34]3 years ago
8 0

Answer:

Note the fragments from DdeI restriction –

I. AA individuals have two copies of normal b-globin allele.

           b-globin allele ----DdeI-----------> 176 bp + 201 bp + 600 bp

Since there are two copies of b-globin allele, the restriction of AA genome would produce 2 copies each of 176 bp, 201 bp and 600 bp fragments.

II. AS individuals have one normal and one mutated copy b-globin allele. So, following fragments would be obtained -

b-globin allele ----DdeI-----------> 176 bp + 201 bp + 600 bp          

b-globin allele ----DdeI-----------> 376 bp + 600 bp

So, for such genotype, four fragments of MW as shown above would be produced.

III. SS individuals have two mutated copy b-globin allele. So, following fragments would be obtained -

b-globin allele ----DdeI-----------> 376 bp + 600 bp

So, for such genotype, two copies each of the fragments of MW as shown above would be produced.

You might be interested in
Predator populations decrease if the number of prey increases. true or false
Vikki [24]
False

Because the predators would have more food if the prey increased
6 0
3 years ago
Give an example of the way sexual selection can cause extreme phenotypes in a population
STatiana [176]
<span>When breeding season arrives, male elephant seals define and defend territories. They collect a harem of 40 to 50 females, which are much smaller than their enormous mates. </span>
7 0
3 years ago
An allosteric protein demonstrates a decrease in its Kg for molecule Y as the concentration of molecule X increases. Based on th
djyliett [7]

Answer:

X is negative heterotropic modulator

Explanation:

In allosteric regulations, modulators are molecules that causes a change in the conformation of an enzyme, hence, resulting a change in enzyme activity. It can lead to a decrease or an increase of the enzyme.  When a molecule decreases the enzyme activity it called a negative modulator, when it increases or activates the enzyme activity, it is called a positive modulator.

A positive or negative modulator can either be homotrophic (substrate acts as modulator) or heterotropic (another ligand acts as modulator).

In the example above, X is negative heterotropic modulator, because the modulator is different from the substrate and it also decreases the enzyme activity.

4 0
3 years ago
What is a vestigial stucture
seropon [69]

Explanation:

Vestigiality is the retention during the process of evolution of genetically determined structures or attributes that have lost some or all of the ancestral function in a given species. Assessment of the vestigiality must generally rely on comparison with homologous features in related species.

7 0
3 years ago
Unlike photosynthesis, cellular respiration occurs in select one:
Anika [276]
B. all eukaryotic cells
hoped this helped!
6 0
3 years ago
Other questions:
  • As the cell plate of a plant cell dissolves what happens next
    12·1 answer
  • ATP is the nucleic acid that
    6·1 answer
  • White blood cells can be found in what liquids?
    12·1 answer
  • If body is moving with a constant velocity its acceleration is?​
    12·2 answers
  • Piaget suggested that children do not develop object permanence until between 8 and 12 months of age. The research of Renee Bail
    14·1 answer
  • "Once the ecological integrity of the Earth is ensured and our basic needs are satisfied, how much is enough?" What is ecologica
    15·1 answer
  • A valid conclusion that can be drawn from this experiment is that spindle fibers break down A.) At the centrioles B.) In the pre
    6·1 answer
  • When observations, over time, repeatedly support an assumption, the assumption comes to be known as a principle true or false
    6·1 answer
  • How does nectar increase the ability of plants to reproduce?
    14·2 answers
  • Can someone plz help me? :(
    12·2 answers
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!