Development of cognitive instruments for use in clinical trials of antidementia drugs:Alzheimer's Disease Assessment Scale (ADAS).
What is Alzheimer's Disease Cooperative Study?
The Alzheimer's Disease Cooperative Study (ADCS) cognitive assessment procedure was created to investigate the validity and reliability of cognitive assessment tools that could be useful additions to the Alzheimer's Disease Assessment Scale (ADAS) or other short batteries used in antidementia medication studies. Patients with mild to moderate AD and elderly individuals with normal cognitive function underwent a battery of five tests at least three times over the course of a year as part of an overall ADCS protocol to create new instruments for use in clinical trials of treatments for Alzheimer's disease (AD). The main result of this inquiry was the discovery of certain prospective additions to the current ADAS that broaden the scope of the cognitive domains and symptom severity levels addressed.
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Answer:
c. synaptic cleft
Explanation:
Ligand-gated cation channels respond by opening due to neurotransmitter binding and located at synaptic clefts.
A potential consequence of cocaine use life-threatening cardiac dysrhythmias.
Cocaine is a powerfully addictive stimulant drug made from the leaves of the coca plant native to South America. Although health care providers can use it for valid medical purposes, such as local anesthesia for some surgeries, recreational cocaine use is illegal. As a street drug, cocaine looks like a fine, white, crystal powder
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