Given what we know about genetics, we can confirm that the case described in the question will be a result of a De Novo mutation.
A De Novo mutation is referred to as the most severe mutation type. This is a mutation that occurs even before embryonic development has commenced. They are usually the result of mutations in the DNA of the germ cells before being fertilized.
These mutations are responsible for a variety of disabilities and can target a wide array of genes to cause these effects.
Genes are the little sections in dna that code for a particular trait also it couldn’t be chromatin because that is the same thing only it is the looser version of chromosomes