When Ashleigh inquired about her family's medical history, she found out that Uncle Albert's mother (Ashleigh's grandmother) als
o had sickle cell disease, but Uncle Allbert's father did not. One of her uncle's six children also had the disease. However, Ashleigh's father, who is Albert's only sibling, did not have sickle cell disease, nor did Ashleigh's mother. Ashleigh's two siblings showed no signs of the disease either. What pattern of heredity does the sickle cell trait follow? Cite evidence from your textbook and its clues to support your conclusion. Based on your answer to this question, what can you conclude about the inheritance of sickle cell disease in Ashleigh's family? What might be Ashleigh's chances of being a carrier of the sickle cell trait?
The sickle cell pattern based on the family history of Ashleigh isan:
Autosomal recessive pattern
Based on the given question, we cam see that in the medical history of Ashleigh's family, most of them have had the sickle cell disease which includes her grandmother, one of her uncle's six children has it too, but her father and grandfather did not have the disease.
With this in mind, the inheritance of the sickle cell disease in the family of Ashleigh is one which is autosomal recessive as it affects some people and doesn't affect others because of the pairing of the chromosome which <em>contains the sickle cell trait.</em>
Before making a decision as to whether you should throw away your baking soda toothpaste or not, you should first determine the basal risk of developing frabjuous cell basocarcinoma. If the chances of developing this are already negligible, then a 700% increase is no cause for alarm.
