In the formation of LTP, the entry of Ca2+ ions into the neuron activates protein kinases, which are the enzymes that contribute to the increased AMPA conductance of the postsynaptic cell.
<h3>What is LTP?</h3>
- LTP or Long-Term Potentiation is a biological process due to which synaptic connections formed between different neurons grow stronger due to frequent activation.
- It can be defined as a way by which the responses of brain change along with the experience thus dealing with learning and memory in the hippocampus.
- It is caused by combining activity of presynaptic and postsynaptic neurons.
- During synapses, Ca2+ is release as a neurotransmitter from the presynaptic neuron. This Ca+ enters the postsynaptic neuron and activates protein kinases.
- The protein kinases increase the activity of AMPA receptors which plays an important role in neurotransmission through glutamate.
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