Answer: a. Baked fish, macaroni with cheese, strained carrots, fruit gelatin, milk
b. Stewed chicken, baked potato with butter, peas, white bread, plain cake, milk...
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Answer:
Symptoms of Creutzfeldt-Jakob disease (CJD) can resemble those of other dementia-like brain disorders, such as Alzheimer's. But Creutzfeldt-Jakob disease usually progresses much more rapidly.
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Okay
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Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
Answer:
Parkinson's disease is a neurological movement disorder. Common symptoms include tremor, slowness of movement, stiff muscles, unsteady walk and balance and coordination problems. There is no cure for the disease.
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Liposuction isn’t considered the best treatment option for obesity. It may not be effective for individuals who can’t lose their weight through exercise and dieting. Obese people almost always gain those pounds back after having it removed through liposuction unless they reduce their calorie intake significantly.
