Answer:
<em>T</em><em>he cytoskeleton</em>
<em>The cytoskeleton functions to create a network organizing the cell components and to also maintain the cell shape. It also provided a uniform movement of the cell and its organelles, by the filament system network found in the cell's cytoplasm</em><em>.</em>
<em>Hope</em><em> </em><em>this</em><em> </em><em>helps</em><em> </em><em>u</em><em>.</em><em>.</em><em>.</em>
Explanation:
Terrestial Animals - Animals which can only live on Land.Examples:- BEAR- CAT- DOG- DEER
Aquatic Animals - Animals which can only live on Water.
Examples:- FISH- OCTOPUSES- LOBSTERS- SEAHORSE
Amphibians - Animals which can live both on land and on water.
Examples:- FROGS- TOADS- SALAMANDERS
Arboreal Animals - Animals which live primarily on trees.Examples:- SQUIRREL- RODENTS- CHAMELEON
Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.
However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.
meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.
We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.
Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.
Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.
Learn more about breast cancer here : brainly.com/question/6747562
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<u>Answer</u>: C) Directional selection occurs when one of two extreme phenotypes is selected for.
The type of natural selection known as directional selection is defined in population genetics in the case in which an extreme phenotype is favored over other phenotype. Thus, the population and its allele frequency will evolve towards this end of the trait spectrum (extreme phenotype). This is also the case illustrated in the graph where the right side represents the extreme phenotype.
Mutations are spontaneous and occur at random however there are some mutagenic agents which increase the chance of this happening such as radiation exposure. If it is a point shift mutation then only a few bases on the dna sequence are changed so only changes a few of the amino acids in that chain (such as inversion of a base). If its a frame shift then the base sequence is altered so much so that every amino acid from after that changes (such as deletion of a base) which can create things such as cri-du-chat syndrome which results from a piece of chromosome 5 is missing. Hope this helps:)
