"climate" does not.
Usually if we comparing "weather" condition with another word, the word would be "climate". Weather is the day to day atmospheric condition, but climate is the overall weather of an area throughout long period of time, such as a decade.
Using it in a sentence, we can see the difference. We would say "the weather today is nice", but we wouldn't say "the climate today is nice". "today" is a short period of time.
Answer:
The correct answer is "both Cdc6 and Cdt1"
Explanation:
The replisome is a complex molecular system that allows for the replication of DNA in yeast. There are multiple genes that participate in the replisome function, however if a researcher finds out that a yeast strain fails to properly form replisomes it is very likely that the genes that might be mutated are both Cdc6 and Cdt1. Cdc6 and ORC are the genes that send the signal to the yeast to start the replisome formation, and Cdt1 is a DNA replication factor that if it is mutated it could cause that yeast is not able to form the replisome.