In the following orbital the lone pair on each N atom is present:
N1: sp3,
N2: p,
N3: p,
N4: sp2,
N5: sp2
Sitagliptin is an anti-diabetic drug used to treat type 2 diabetes and is marketed under the brand names Januvia and others. One carbon atom has no pi bonds, while the first nitrogen atom is linked to two hydrogen atoms. It thus possesses sp3 hybridization.
The second nitrogen atom possesses a single pair of electrons and is bound to three other atoms. It is hence sp2 hybridized. The nitrogen atoms in positions 3, 4, and 5 have sp2 hybridization.
The lone pair of nitrogen in the first nitrogen atom is in the sp3 orbital. The second and third nitrogen atoms' only pair of electrons are in p-orbitals. The fourth and fifth nitrogen atoms' lone pair of electrons are in sp2 orbitals.
Here is another question with an answer similar to this about Sitagliptin: brainly.com/question/28275161
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Osteoporosis affects the a) skeletal body system
Answer:
Homeostasis can be defined as the natural mechanism of the body by which the internal temperature of the body is maintained.
This phenomenon is important for the normal metabolism and functioning of the body.
Whenever the body encounters any change in the outer environment, the body tries to cope up with the conditions by maintaining a proper internal temperature inside the body.
Example: shivering of body is a normal response during cold environment to maintain the internal temperature of the body.
Answer:
Thyroid nodules is a condition where lumps form in the thyroid gland.
Some symptoms may include difficulty breathing, difficulty swallowing, and sudden weight loss.
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