Soils are formed through the interaction of five major factors: time, climate, parent material, topography and relief, and organisms. The relative influence of each factor varies from place to place, but the combination of all five factors normally determines the kind of soil developing in any given place.
The result of this mutation on the target is that particular hormone will have no effect on the target cell. In addition, down regulation is the constant high absorption of a hormone that can cause a reduction in the quantity of its receptors.<span />
