Answer:
Option A, a drug to treat high blood pressure that reversibly inhibits an enzyme catalyzing production of a chemical that causes blood vessels to contract
Explanation:
The complete question is
If you were working for a pharmaceutical company as part of a drug discovery team, which of these enzyme inhibitors would you suggest as a productive avenue for drug development?
a) a drug to treat high blood pressure that reversibly inhibits an enzyme catalyzing production of a chemical that causes blood vessels to contract
b) a drug to treat diabetes that irreversibly inhibits an enzyme in the metabolic pathway to synthesize glucose
c) a compound that acts as a competitive inhibitor for a digestive enzyme produced only in the presence of certain foods
d) a compound that inhibits enzymes by significantly changing the ph throughout the body
Solution
Productive avenue of a drug simply means producing an drug that not only treats the main disease or disorder but also functions to inhibit the causative agent activity. In case of option A, both the objectives of producing drug are met and hence it is the right choice.
High blood pressure usually affects the blood vessels by narrowing them and in severe cases may rupture them. If a drug as stated in option A is produced, it will not only rectify the effects of high blood pressure but will also prevent the blood vessels from narrowing by inhibiting the activity of enzymes responsible for producing chemical that leads to blood vessel contraction.
Hence, option A is correct
Answer:
The correct answer is ''METAPHASE I.''
Explanation:
Metaphase I is the stage in which chromosomal studies are generally performed, because its morphology is very clear. The chromosomes, moved by the mitotic spindle, are placed in the center, between the two asters and form the so-called metaphase plate, in which the chromosomes are positioned in such a way that the kinetochore of each sister chromatid are oriented towards the opposite poles. Keeping chromosomes on the cell equator implies a balance between the forces of the microtubules that tend to move the kinetochores toward opposite poles, so positioning them in the center involves a great deal of energy.In each kinetochore, between 20-30 microtubules can be anchored, which exert traction force towards the pole from which they come, so the metaphase plate is maintained by the balance between the opposite forces of the poles on the chromosomes, which hold their sister chromatids by centromeric cohesin.
The notable
hardness of bone is attributed to the presence of inorganic hydroxyapatites.
Due to the calcium salts deposited in it, resulting to the hardness. The
abnormal hardness of bone, which allows it
to resist the compression.
Answer:
B. Bacteria can exchange genes for resistance to antibiotics in this way.
Explanation:
Even though conjugation requires cell-to-cell contact, it can occur between distantly related bacteria
