Answer:
The main function of the RB protein is to inhibit the transition from the G1 to S phase. Its activity depends on its phosphorylation state: if RB is not phosphorylated (active state), it is bound to the transcription factor E2F, preventing its translocation to the nucleus and the activation of genes necessary for DNA synthesis; and if it is phosphorylated, by cyclin-CDK complexes, E2F is released and cell proliferation occurs.
Explanation:
Retinoblastoma (Rb) was the first tumor suppressor described and, as we know today, mutations in its structure determine a large number of cancers. Structurally, we speak of a large and multifunctional protein; which is organized in different domains. The activity of this protein is regulated, mainly, by phosphorylation at multiple sites described over the years and is involved in control mechanisms of the cell cycle, apoptosis and senescence.
Answer:
A cell that results from the fusion of sperm and ovum is called a zygote. The process of fusion of sperm and ovum is called fertilization.
Answer:
Masks and Vaccines (RNA vaccines but normal vaccines help as well)
Explanation:
Masks: As we can tell cities that have a mask mandate have lower corona numbers
Vaccines: Vaccines give your body the antibodies that it needs to protect your body from infection without the virus. RNA vaccines are better than the normal vaccines because they are going to be produced faster than normal vaccines
Answer:
C
Explanation:
A toboggan is a simple sled traditionally used by children. It is well adapted to sliding down open slopes, where its large surface rides easily on loose, fluffy snow.
Answer:
b. Frank received the mutant chromosome from his father. Nondisjunction occurred in his father during the first meiotic division.
Explanation:
As you can see in the question above, Frank has Klinefelter syndrome which causes him to have normal skin patches and skin patches without sweat glands. Her mother has completely normal hair, which may indicate that the defective gene was not supplied by her. In addition, Frank's father has anhydrotic ectodermal dysplasia, an X-linked condition where the skin does not contain sweat glands.
Although Frank's father's defective gene is linked to the X chromosome, it is likely that Frank inherited the defective gene from his country. This may have occurred because during meiosis I, his father's genes did not show disjunction. As a result, Frank presents a mosaic of his phenotype, because an inactivation of the X chromosome occurred.