Muscle cramps are caused when the muscle takes longer than normal to relax after a contraction. During contraction, the myosin heads attach on their binding sites on the actin filament and pulls on the filament hence shortening the sarcomeres. For the myosin head to release its binding site on the actin filament, ATP attaches to an active site on the myosin and is hydrolyzed to ADP and Pi. This causes relaxation after a contraction cycle. Cramps, therefore, may be due to depletion of ATP molecule in the muscles cells.
Another reason for cramps may be a high amount of calcium in the muscles that bind to troponin on the actin filaments. This exposes the myosin binding sites longer hence promotes the formation of cross-bridge even when the contraction of the muscle is not intended anymore.
Is that the whole question please be more specific
Answer:
This can be evaluated with DNA test- by comparing the mitochondrial DNA (mtDNA)of the Tsar family with the woman-Anastasia. <u>Maternal DNA is inherited uninterrupted from generation to generation
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Explanation:
The living consort of Queen of Elizabeth ,Prince Philip, <u>is a grand nephew of Tsar Nicholas 11.</u> They shared the same maternal ancestry.
Therefore, his mitochondrial must be maternal, and compatible with that of the Tsar Nicholar. Male children always inherit maternal mitochondria (mtDNA)and passed from generations to generation.
T<u>he blood samples of prince Philip can be taken, to extract the mtDNA,and matched with the sample of mtDNA obtained from the exhumed bodies of the Tsars,</u><u> </u>to reaffirmed the compatibility of the ancestry .
If sample of the compatible mtDNA, from price Phillip was compared with the mtDNA of the woman who claimed to be Anastasia, her claim can be validated.
Matched sample shows she was the daughter, while negative result proves otherwise.
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