Devise a three‑step synthesis of the product from 1‑methylcyclohexene
2 answers:
Three step synthesis of the product from 1‑methylcyclohexene includes epoxide formation, nucleophilic attack and oxidation of -OH group.
<h3>What is synthesis reaction?</h3>Synthesis reactions are those reactions in which formation of new product takes place by the rearrangement or combination of reactant molecules.
Given question is incomplete so the complete pic of the question is attached below. In the given reaction reagents 1, 2 and 3 are used is C₆H₅CO₃H in CH₂Cl₂, C₆H₅Li in ether and PCC in CH₂Cl₂ respectively.
In the tree step synthesis process, in the first step formation of epoxide takes place, in the second step attack of nucleophile on epoxide takes place and finally in the third step oxidation of hydroxyl group to ketone group takes plce.
Hence 3 step synthesis includes epoxide formation, nucleophilic attack and oxidation of -OH group.
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The final temperature : 78.925°C
<h3>Further explanation </h3>Heat can be calculated using the formula:
Q = mc∆T
Q = heat, J
m = mass, g
c = specific heat, joules / g ° C
∆T = temperature difference, ° C / K
Energy releases = 130 kcal = 130 x 4.18 kJ=543.4 kJ
The final temperature :
Final temperature :
ΔT=final-initial
51.925°c=final-27°c
final = 51.925+27=78.925°C