Question

What made it possible for the Mississippi River Valley to support large cities?

Answer 1

Answer: Moving their goods down river to the Mississippi, to New Orleans, and then by sea to the cities on the Eastern Seaboard was cheaper and actually easier which made it a popular  location for trade and  to build cities . Also The  Mississippi River provided  water source  to the  people  whom  lived in the area.

Hope it helps <3 (Please tell me  if you need anymore help)

Answer 2

The big river was helpful to many people and other in the city it’s was basically a big source of water near by