The risk-benefit assessment is widely used in the field of medicine. Apart from being therapeutic, it is a known fact that synthetic medicines also carry side effects. However, if the healthcare provider believes that a certain medication outweighs the side effects, then he or she will prescribe the said medicine. This is the very reason why the concept of risk-benefit is truly vital.
1) Physiological need, such as needs for food, sleep, and air
2) Safety or the needs for security and protection
3) Belonging and love
4) Needs for self esteem and self respect
5) Needs concerning creative self growth, engendered from fulfillment of potential and meaning in life
The ends of the femur are covered in a smooth, slippery substance called articular cartilage. This cartilage protects and cushions the bone when you bend and straighten your knee. The normal anatomy of the knee.
If a proteins shape was changed it may be able to do its function to do being unable to fit in all blood vessels/arteries and the shape change may of hindered its capability of carrying nutrients it needs to transport, etc.
for example:
If a hemoglobin (red blood cell) shape changed, (this is normally called sickle cell) the red blood cell would be to unable to travel through the body with ease and easily clog bloodstreams. Also, the hemoglobin will not be able to transport as much oxygen throughout the body.