Answer: The ocean is one of Earth's most valuable natural resources. It provides food in the form of fish and shellfish about 200 billion pounds are caught each year. It's used for transportation both travel and shipping. It provides a treasured source of recreation for humans
Explanation:
Answer:Dogs have many charateristics and it depends on what dog you own
Explanation:
Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.
However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.
meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.
We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.
Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.
Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.
Learn more about breast cancer here : brainly.com/question/6747562
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Answer;
-Reduce the chance of errors in correspondence
-Easier to use for converting between units while measuring
-Make communication easier between scientists comparing data
Explanation;
-The metric system is a system that is based on joining one of a series of prefixes, including kilo-, hecto-, deka-, deci-, centi-, and milli-, with a base unit of measurement, such as meter, liter, or gram.
-Since the metric system is a decimal system of weights and measures it is easy to convert between units simply by multiplying or dividing by 10, 100, 1000, etc.
-It is an alternative system of measurement used in most countries, as well as in the United States.
