The main objective of phase 3 trials is to verify the therapeutic action of a new substance in a large number of patients, essentially to determine the risk/benefit ratio. Before phase 3, the substance is not regarded as a drug, but after a positive phase 3 trial it becomes a drug.
Answer:By the 1700s, dentistry had become a more defined profession. In 1723, Pierre Fauchard, a French surgeon credited as the Father of Modern Dentistry, published his influential book, The Surgeon Dentist, a Treatise on Teeth, which for the first time defined a comprehensive system for caring for and treating teeth. Additionally, Fauchard first introduced the idea of dental fillings and the use of dental prosthesis, and he identified that acids from sugar led to tooth decay.
Dentistry is one of the oldest medical professions, dating back to 7000 B.C. with the Indus Valley Civilization. However, it wasn’t until 5000 B.C. that descriptions related to dentistry and tooth decay were available. At the time, a Sumerian text described tooth worms as causing dental decay, an idea that wasn’t proven false until the 1700s!
In ancient Greece, Hippocrates and Aristotle wrote about dentistry, specifically about treating decaying teeth, but it wasn’t until 1530 that the first book entirely devoted to dentistry—The Little Medicinal Book for All Kinds of Diseases and Infirmities of the Teeth—was published.
Explanation:
1. why are you considering leaving your current job?
2. where do you see yourself in 4 years?
3. what interested you in a position with MOI?
those are just a couple i’ve seen :)
Answer:
an idiom
Explanation:
not meaning the literal thing you said,
just as those who die do not actually kick a bucket or calendar, it is a phrase to use that means someone has died
hope this helps:)