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2 years ago

Which of the following is associated with schizophrenia?

Biology

1 answer:

babymother [125]2 years ago

7 0

Less gray matter is associated with schizophrenia and is denoted as option B.

<h3>What is Grey matter?</h3>

These are usually darker tissues which are found in the brain and spinal cord. They contain a rich network of neurons present.

This is therefore the reason why schizophrenia is associated with mental health.

Read more about Grey matter here brainly.com/question/13782390

#SPJ1

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The CRISPR/Cas9 system can cleave genomic DNA at sequences other than the desired target, a phenomenon referred to as off target

Deffense [45]

Answer:

The minimum length of a sgRNA sequence to avoid off target cleavage by the CRISPR/Cas system in the fly fruit genome is 14 bases

Explanation:

We are trying to use the CRISPR/Cas system to cleavage the genome of the fruit fly (which is 1.4x10^8 bp long). Also we desire the cleavage to be unique. That means we need a target sequence long enough to be able to assume it will only appear once in the genome.

First, we should think that in every position, we can find one out of four different nucleotide (A, C, T, G). So, the probability of getting a sequence of a given length "n" will be (1/4)^n (We are assuming that the probability of finding a nucleotide in the position "i", it's independent of the nucleotide we find in any other position "j").

Also, to know how many times a sequence will appear in a genome (the expected value of occurrence), we must multiply the probability of that sequence to randomly occur by the length of the genome. For our specific example, the number of occurence of a sequence of length "n" is:

nºoccurence=[(1/4)^n]*1.4*10^8

But in this case, what we want is the expected number of times the sequence will appear to be 1, and we want to obtain the length of the target sequence (n).

Given the information above, we know that:

[(1/4)^n]*1.4*10^8 =1

[(1/4)^n]=(1/1.4*10^8)=1.4*10^-8

Then, if we want to calculate n, we can use logarithms and its properties to get:

log[(1/4)^n]=log[1.4*10^-8]

n*log[(1/4)]=log[1.4*10^-8]

n=log[1.4*10^-8]/log[(1/4)] => n=13.29 approximately.

As the sequence needs to have a natural number of elements, we can conclude that using a target sequence of a minimum of 14 bases with the CRISPR/Cas system in the fly fruit genome should be enough to avoid off target cleavage.

3 0

3 years ago

A commercial advertising a diet pill says it is scientifically proven to help you lose weight. It is recommended by a doctor who

lisov135 [29]

Answer:

No it hasn't been recommended by a doctor.

Explanation:

This is considered pseudoscience because there is no proof that it has been scientifically proven.

6 0

3 years ago

Read 2 more answers

Is composed of the organic solids collected during the wastewater treatment process?

Daniel [21]

I think the answer is sludge.

Hope this helped.

4 0

3 years ago

4) A homozygous groucho fly ( gro, bristles clumped above the eyes) is crossed with a homozygous rough fly (ro, eye abnormality)

docker41 [41]

Answer and Explanation:

A homozygous groucho fly ( gro, bristles clumped above the eyes) is crossed with a homozygous rough fly (ro, eye abnormality).

The F1 females are testcrossed, producing these offspring: groucho 518 rough 471 groucho, rough 6 wild-type 5 1000 a) What is the linkage distance between the two genes? B) Plot the genes on a map c) If the genes were unlinked and the F1 females were mated with the F1 males, what would be the offspring in the F2 generation?

1st cross:

Parental) grogro ro+ro+ x gro+gro+ roro

F1) gro+gro ro+ro

2nd cross:

Parental) gro+gro ro+ro x grogro roro

Gametes) gro+ro+ gro ro

gro+ro gro ro

gro ro+ gro ro

gro ro gro ro

Punnet square)

gro+ro+ gro+ro gro ro+ gro ro

gro ro gro+gro ro+ro gro+gro roro grogro ro+ro grogro roro

F2)

0.518 grogro ro+ro (518 individuals)

0.471 gro+gro roro (471 individuals)

0.006 grogro roro (6 individuals)

0.005 gro+gro ro+ro (5 individuals)

Total number of individuals 1000

Note: These frequencies were calculated dividing the number of individuals belonging to each genotype by the total number of individuals in the F2.

To know if two genes are linked, we must observe the progeny distribution. If individuals, whos genes assort independently, are test crossed, they produce a progeny with equal phenotypic frequencies 1:1:1:1. If we observe a different distribution, that is that phenotypes appear in different proportions, we can assume that genes are linked in the double heterozygote parent.

In the exposed example we might verify which are the recombinant gametes produced by the F1 di-hybrid, and we can recognize them by looking at the phenotypes with lower frequencies in the progeny.

By performing this cross we know that the phenotypes with lower frequencies in the progeny are groucho, rough and wild-type. So the recombinant gametes are gro+ro+ and gro ro, while the parental gametes are gro+ro and gro ro+.

So, the genotype, in linked gene format, of the double heterozygote individual in the F1 is gro+ro/gro ro+.

To calculate the recombination frequency we will make use of the next formula: P = Recombinant number / Total of individuals. The genetic distance will result from multiplying that frequency by 100 and expressing it in map units (MU). One centiMorgan (cM) equals one map unit (MU).

The map unit is the distance between the pair of genes for which one of every 100 meiotic products results in a recombinant product.

The recombination frequency is:

P = Recombinant number / Total of individuals

P = 6 + 5 / 1000

P = 11 / 1000

P = 0.011

The genetic distance between genes, is 0.011 x 100= 1.1 MU.

Genetic Linkage Map:

Parental Phenotypes)

-----gro+------ro---- -----gro------ro+----

----- gro ------ro---- ---- gro------ ro ----

Recombinant phenotypes)

-----gro+------ro+---- -----gro------ro----

----- gro ------ ro---- -----gro------ro----

If the genes were unlinked and the F1 females were mated with the F1 males, the offspring in the F2 generation would have been

4/16 = 1/4 gro+gro ro+ro

4/16 = 1/4 gro+gro roro

4/16 = 1/4 grogro ro+ro

4/16 = 1/4 grogro roro

Their phenotypic frequencies would be 1:1:1:1 related.

7 0

3 years ago

Care sunt animalele care hibernează? Vă rog repede! Dau 100 de puncte :)

ankoles [38]

Answer:

<h3>MEE TOO I DONT UNDERSTAND THIS QUESTION!☡</h3>

3 0

3 years ago