Question

Describe how an enzyme’s shape changes as it binds to its substrate. Describe a condition under which an enzyme might to be able to bind to its substrate.

Answer 1

The enzyme’s shape changes as it binds to its substrate because enzymes are highly specific, the main reason for enzyme’s shape changes as it binds to its substrate is temperature, pH and time.

Why an enzyme is so specific for its substrate?

Is due to the fact that the enzyme's active site has a complementary format to its substrate, promoting a contract, like a key that fits perfectly in a given fixation.

Substrate is the reagent on which an enzyme acts. When an enzyme binds to its substrate, the enzyme-substrate complex is formed. This binding takes place in a specific region, called the active site.

One exemple of an enzyme changing it's shape to binds to a substrate is pepsine. Pepsine changes it's shape to bind to proteins in the stomach and break them down into smaller peptides.

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