<u> The </u><u>equilibrium </u><u>constants for the two reactions are CO binds Hb </u><u>140 times</u><u> more strongly than O₂</u>
What is equilibrium reaction in chemistry?
- In a chemical reaction, chemical equilibrium is the state in which both the reactants and products are present in concentrations .
- which have no further tendency to change with time, so that there is no observable change in the properties of the system.
CO has a greater affinity for hemoglobin than oxygen does. It displaces oxygen and quickly binds, so very little oxygen is transported through the body cells.
Since CO binds more strongly equilibrium constant (Kco) will be higher than Ko2.
Here are the equation for equilibrium constant.
When binds with hemoglobin (Hb)
1) [ Hb + O₂ ⇄ HbO₂ ] ÷ kO₂ = [ HbO₂ ]/ [ Hb] [ O₂]
2) [ Hb + CO ⇄ HbCO ] ÷ kco = [ HbCO] / [ Hb] [CO]
Conclusion -
Since CO binds Hb 140 time is more strongly than O₂
kCO >> kO₂ or { kCO / kO₂ ≅ 140 }
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