It is important to maintain the ph of blood and tissue fluids within normal limits because the structure and function of macromolecules are pH sensitive, and even little variations from normal pH can cause metabolic processes to shut down.
Tissue fluid is found in the spaces around cells. It comes from substances that leak out of blood capillaries (the smallest type of blood vessel). It helps bring oxygen and nutrients to cells and to remove waste products from them.
The two forms of connective tissue in this subcategory are blood and lymph. Both are fluid rather than solid, and neither has the network of extracellular protein fibers that other types of connective tissue have.
Diffusion and filtration processes create tissue fluid from plasma. This fluid fills the intracellular space and serves as a link in the transmission of nourishment, gases, and metabolic end products between blood capillaries, tissue fluid, and lymph.
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