All categories

2 years ago

Dual Antiplatelet Therapy Using Cilostazol in Patients With Stroke and Intracranial Arterial Stenosis

1 answer:

4 0

Background- In patients with intracranial artery stenosis, a long-term advantage of dual antiplatelet therapy (DAPT) over single antiplatelet therapy (SAPT) for the prevention of recurrent stroke has not been proven. We studied patients with intracranial arterial stenosis who were enrolled in the Cilostazol Stroke Prevention Study for Antiplatelet Combination trial, a randomized controlled trial in high-risk Japanese patients with ischemic stroke, to compare the efficacy and safety of DAPT with cilostazol and clopidogrel or aspirin to those of SAPT with clopidogrel or aspirin. Techniques and Outcomes In patients with ischemic stroke with symptomatic or asymptomatic intracranial arterial stenosis of at least 50% in a major intracranial artery, we compared the vascular and hemorrhagic events between DAPT and SAPT.

Patients were divided into two groups: 275 were given DAPT, while 272 were given SAPT. In contrast to SAPT, which had a higher risk of serious or life-threatening bleeding, DAPT had a lower risk of ischemic stroke (hazard ratio [HR], 0.47; 95% CI, 0.23-0.95); and a composite of stroke, myocardial infarction, and vascular mortality (HR, 0.48; 95% CI, 0.26-0.91). Conclusions In patients with intracranial artery stenosis following stroke, DAPT using cilostazol was superior than SAPT using clopidogrel or aspirin for the prevention of recurrent stroke and vascular events without raising bleeding risk.

<h3>What is stroke?</h3>

When anything prevents blood flow to a portion of the brain or when a blood artery in the brain bursts, a stroke, also known as a brain attack, happens. The brain either ages or suffers harm in both scenarios. A stroke may result in permanent brain damage, chronic disability, or even fatality.

To learn more about stroke with the help of given link:

brainly.com/question/26482925

#SPJ4

You might be interested in

Through the value-based purchasing initiative enacted by the Affordable Care Act, what has transformed from a passive payer to a

ivolga24 [154]

Answer: Option 1) Medicaid

Explanation:

Through the value based purchasng initiative enacted by Affordable Care Act, in US Healthcare, decided to expand the services of medicaid.

Medicaid provide government sponsored insurance program to the individuals with low income. Medicaid expansion involves that it wil provide long term health care services and pay all the health benefits for more than 70 million people.

Medicaid expansion become efficient health care program as it covers populations with low income, including young children, pregnant women and physically or mentally disable adults. Peopleadded in this program on different eligibility varies widely among states to meet all the states with minimum federal need.

Hence, the correct option is 1) Medicaid.

6 0

3 years ago

Michael's training diet may be low in several micronutrients. Deficiencies of ______ can lead to fatigue.

NikAS [45]

Answer:

everything except calcium

Explanation:

6 0

3 years ago

The following compound is a(n) ____. a. industrial solvent b. amino acid c. vitamin d. monomer for polystyrene

Debora [2.8K]

Answer:

Option B== > Amino acid

Explanation:

KINDLY NOTE that the compound in the question is attached below as a picture.

From the diagram in the picture, the compound contains an aryl group, Amine functional group and a carboxylic functional group. An Amino acid compound is a compound that has carboxyl group and the amine group which makes the answer to the question to be option 'b' that is Amino acid.

Polystyrene has formula like this:(C8H8)n, there is no amine functional group attached and there is no carboxyl functional group either which makes polystyrene not to be the answer. This the same case with vitamin D which has which has hydroxyl functional group and not carboxylic nor does it has amine functional group. Although it has been revealed through series of researches that Amino acid are good solvent for Carbondioxide, the most correct option for this question will be on identifying the correct compounds with reference to their functional groups.

3 0

3 years ago

kap26 [50]

The most natural approach to get enough Vitamin D is through regular sun exposure. Aim for 10 to 30 minutes of midday sunshine many times per week to maintain appropriate blood levels. Those with darker complexion may require a little more.

<h3>What is Vitamin D ?</h3>

According to the National Institutes of Health, two to three times per week, between five and thirty minutes of unprotected sun exposure to your face, arms, legs, or back between the hours of 10 a.m. and 3 p.m. is sufficient for your body to produce all of the D3 it requires. Vitamin D synthesis can be inhibited by sunscreen.

Your skin tone, age, dietary habits, and the environment in which you reside all have a role. In general, scientists believe that 5 to 15 minutes, or up to 30 minutes if you have dark skin, is approximately right to get the most benefit without endangering your health. If you wear sunscreen, you can spend more time outside and yet receive the same result.

In the continental United States, UV rays are typically highest between 10 a.m. and 4 p.m. (9 a.m. to 3 p.m. standard time). The UV Index predicts each day's UV ray intensity. Avoid overexposing your skin to the sun if your area's UV index is 3 or higher.

To know more about Vitamin D please click here : brainly.com/question/4551554

#SPJ13

6 0

1 year ago

13. Describe all of the hormonal influences on skeletal growth and development.

ss7ja [257]

Answer:

The growth hormone/IGF-1 system stimulates both bone-resorbing and bone-forming cells, but bone formation is the dominant effect, resulting in increased bone mass. Thyroid hormones boost the energy production of all cells in the body, including bone cells.

6 0

2 years ago