Question

ardiac muscle cells rely mainly on fatty acids and glucose from the blood to produce ATP. Both glucose and fatty acids are catabolized to acetyl CoA before undergoing further metabolism. Select all the enzymes and pathways utilized by cardiac muscle to oxidize organic compounds in order to produce ATP. PDH complex glycolysis gluconeogenesis citric acid cycle

Answer 1

It is now well established that oxidation of other energy substrates, such as ketones and branched chain amino acids (BCAAs), can also contribute to energy production in the heart, despite the fact that mitochondrial fatty acid and carbohydrate oxidation is the major source of ATP production in the heart.

Cells must evaluate their metabolic condition in response to a dynamic nutritional environment to determine whether to grow, survive, or perish. When communicating metabolic information to their protein and nucleic acid counterparts, these tiny molecule metabolites are crucial. The processes by which metabolites have an impact on cellular regulatory mechanisms are still largely unknown, despite growing knowledge of this reciprocal interplay.

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