Risks of deep vein thrombosis (DVT) and pulmonary embolism (PE) in chronic pancreatitis (CP) are <u>unclear</u>.
The CP cohort showed a 2.95-fold greater adjusted hazard ratio (aHR) for DVT and a 4.51-fold greater aHR for PE than the non-CP cohort. Substantial risks of DVT and PE were evident in patients with CP aged < 55 years.
The CP cohort with comorbidities showed increased risks of DVT and PE as compared with the non-CP cohort.
Hence the risks of DVT and PE are significantly higher in CP patients than in the general population.
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Both cancers involve the same genomic change in homologous chromosomes. The only difference is that the first mutation is inherited and the second is somatic in familial cancer, whereas in sporadic cancer both mutations are somatic.