Question

Why is the alternative pathway of complement useful in the early stages of an infection?

Answer 1

The alternative pathway of complement useful in the early stages of an infection because It's faster than the other complement pathways.

The alternative pathway is one of three complement pathways that opsonize and kill pathogens. This pathway is activated by viruses, fungi, bacteria, immunoglobulin A  and forms an important part of the defense mechanism independent of the immune response.

The alternative pathway (AP) is slowly activated spontaneously by hydrolysis of the internal C3 thioester bond [12–14] and further triggered by contact with various proteins, lipids and carbohydrate structures on microorganisms and other foreign surfaces [1, 15].

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