Entire muscles are encased in the epimysium. The perimysium, which is connected to the epimysium, separates groups of muscle fibres into fasciculi. Individual muscle fibres are encircled by a delicate network of connective tissue fibres, blood arteries, lymphatic vessels, and nerves called the endomysium.
The collagen fibres of tendons are made of endomysium, perimysium, and epimysium, and they serve as the tissue link between muscles and bones by indirect attachment. Intermittent perimysial junction plates serve as its connection to the perimysium.
The perimysium, which surrounds bundles of muscle fibres, the endomysium, which surrounds individual muscle fibres, and the epimysium, which surrounds the muscle, are the three scale levels at which connective tissue of the muscle may be identified.
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