In order to use amino acids as fuels, amino acid metabolism must occur. This process results in the formation of 2-oxo-acids.
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What is amino acid metabolism? </h3>
The excess proteins/amino acids in the body are to be broken down or catabolized as there is no mechanism for the storage of amino acids in the human body. Different amino acids have different mechanisms of catabolism.
Based on their catabolism process, amino acids are categorized into two types.
1. Glucogenic amino acids - The amino acids which can be converted into glucose, pyruvate, and intermediates of the TCA cycle are called Glucogenic amino acids. These intermediates are converted to 2-oxo-acids.
2. Ketogenic amino acids - These are either converted to fat, Acetyl CoA, or AcetoacetylCoA. These condense with 2-oxo-acids and the net gain is zero.
Therefore, amino acid metabolism results in the formation of 2-oxo-acids.
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