Sulfa drugs work on folic acid biosynthesis.
<h3>Sulfa drugs :</h3>
Dihydropteroate synthase is a particular enzyme that sulfa medicines bind to and block (DHPS). The creation of the important vitamin folate depends on this enzyme. Folate is a nutrient that mammals obtain from their diet, but bacteria must make it.
Any member of a class of synthetic antibiotics with the sulfanilamide molecular structure is referred to as a sulfa medication, sometimes known as a sulfonamide. The first systematically utilized chemical compounds to treat and prevent bacterial infections in humans were sulfa medicines. Due to the emergence of safer, more effective antibiotics as well as the rise in drug resistance, their use has decreased. Sulfonamides are still used, but mostly to treat and prevent infections from burns and urinary tract infections. Additionally, they are employed in the management of some types of malaria.
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