<h3><u> Top challenges for Hollywood managers:</u></h3>
Challenges that face Hollywood managers include finding the right film executives who will ensure the success of the production and the company. Another challenge is finding the right cast that will relate to the public which will in turn increase the company’s profit.
There is also a challenge of making stories that will bring in audience and generate revenue over time. Data mining is very important in Hollywood to analyse the success and failure of the company. Other industries which face similar problems include governments, technology companies, etc.
Answer:
Elevate the arm, cover the wound with a dressing and apply pressure
Explanation:
Answer:
The correct option is;
D. The use of witchcraft to curse a person
Explanation:
The power of sorcery is widely believed among the Baloch, to be a negative power with the ability to cause many types illnesses, diseases and other forms of misery
By sorcery, supernatural power is used by persons to bring about losses, diseases, or death. When persons fall ill and the ailment is attributed to sorcery, the person is treated by a person that can ill through the powers available in a religion or by a sorcerer through ritualistic spells to cast out the evil (spirits and/or incantations)
Answer:
The asnwer is A) cardiogenic
Explanation:
Patient with severe anterior chest trauma with 88 pulse per minute, tachypneic, 92/68 pressure and peripheral cyanosis is presenting a cardiogenic shock. We talk about cardiogenic shock when the heart is unable to pump enough blood to the entire body that is needs to. It is caused by serious cardiac complications, such as severe trauma to the heart with damage to its structures, such as tendons, cardiac muscles or wall, and also the accumulation of fluid around it (cardiac tamponade).
Answer:
Okay
Explanation:
Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
