Question

True or false: the tubuloglomerular feedback mechanism acts as a 'backup' mechanism to the myogenic mechanism in response to increased systemic blood pressure.

Answer 1

True

• Tubuloglomerular Feedback (TGF) is a type of internal feedback system in kidney physiology.
• The glomerulus in each nephron receives information from the renal tubules, which are located downstream in the tubular fluid (an upstream area).
• One of the processes the kidney utilizes to control glomerular filtration rate is tubuloglomerular feedback (GFR).
• An elevated distal tubular sodium chloride concentration results in a basolateral release of adenosine from the macula packed cells, and this process is known as purinergic signaling.
• This starts a chain of events that eventually raises the GFR to the proper level.

What is tubuloglomerular feedback mechanism?

A feedback system found inside the kidneys is called tubuloglomerular feedback in the study of renal physiology. The glomerulus in each nephron receives information from the renal tubules.

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