In a three-dimensional model, collagen type I gels are used to hold C6 astrocytoma spheroids of specific sizes.
Laminin, fibronectin, and collagen type IV are extracellular matrix proteins that do not significantly affect invasive activity, whereas hyaluronic acid lowers and myelin from the human central nervous system promotes invasion.
The subpopulation of cancerous cells that are dispersed far from the primary tumor mass must be considered in new treatments for malignant gliomas. The spheroid invasion model could offer detailed explanations of how these invasive cells behave.
<h3>What is C6 Astrocytoma spheroid ?</h3>
A rat glioma cell line known as C6 can generally mimic the rapid development, high vascularization, and highly infiltrative nature of glioblastoma multiforme.
<h3>What is Collagen?</h3>
Amino acids make up the protein molecules that make up collagen. It gives connective tissues' extracellular space structural support. It is the ideal matrix for skin, tendons, bones, and ligaments because of its stiffness and resistance to stretching.
To know more about Collagen please click here : brainly.com/question/14387059
#SPJ4
