Question

How could you increase the magnitude of excitatory postsynaptic potentials (EPSPs) generated at a synapse? A. Increase sodium-potassium pump activity. B. Increase K⁺ permeability. C. Increase Na⁺ permeability. D. All of the listed responses are correct.

Answer 1

The correct option is C. Increase Na⁺  permeability

An excitatory postsynaptic potential(EPSP) is generated when positively charged ions flow into the postsynaptic cell due to the opening of ligand-sensitive channels. Due to more influx of sodium ions the positive charge inside the neural cell increases and so, it becomes depolarized.

The function of the sodium-potassium pump is to maintain the osmotic equilibrium and membrane potential in the cells. As the ions sodium and potassium move against the concentration gradient, this pump helps to maintain their flow.

K⁺ ions are present in greater amounts inside the cell and  Na⁺ ions are present in greater amounts on the outside. If the permeability for K⁺  increases the membrane inside will become even more negative and it will lead to hyperpolarisation of the neuron.

Learn more about Excitatory postsynaptic potential here: brainly.com/question/12975351

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