A subset of MHC molecules known as Class II of the Major Histocompatibility Complex (MHC) is often only found on specific antigen-presenting cells such as dendritic cells, mononuclear phagocytes, specific endothelium cells, thymic epithelial cells, and B cells.
<h3>Do macrophages contain MHC 2?</h3>
In order to deliver Listeria monocytogenes to T cells for phagocytic processing, class II MHC molecules are found in macrophage lysosomes and phagolysosomes.
<h3>Are macrophages MHC-positive?</h3>
Exogenous antigens can be processed by macrophages and displayed on MHC molecules.
<h3>Which cells possess MHC 1 vs. 2?</h3>
All nucleated cells contain MHC I glycoproteins. Specialized antigen-presenting cells are the only ones to contain lls.
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