<span>The hormone INSULIN is released from the pancreas when blood glucose is elevated above a normal range.
This hormone regulates your blood sugar level. When your blood glucose is elevated above a normal range, the insulin is released from the pancreas. It then attaches itself to the cells and signals them to absorb the excess sugar from the blood stream.
If your blood sugar level is low, insulin signals the release of stored sugar to the blood stream to maintain the normal level of your blood glucose.</span>
Convection Current
This happens when there is a noteworthy contrast in temperature between two sections of a liquid. At the point when this temperature distinction exists, hot liquids rise and cool liquids sink, and after that streams, or developments, are made in the liquid
The DNA polymerases are enzymes that create DNA molecules by assembling nucleotides, the building blocks of DNA. These enzymes are essential to DNA replication and usually work in pairs to create two identical DNA strands from one original DNA molecule. During this process, DNA polymerase “reads” the existing DNA strands to create two new strands that match the existing ones.
Every time a cell divides, DNA polymerase is required to help duplicate the cell’s DNA, so that a copy of the original DNA molecule can be passed to each of the daughter cells. In this way, genetic information is transmitted from generation to generation.
Before replication can take place, an enzyme called helicase unwinds the DNA molecule from its tightly woven form. This opens up or “unzips” the double stranded DNA to give two single strands of DNA that can be used as templates for replication.
DNA polymerase adds new free nucleotides to the 3’ end of the newly-forming strand, elongating it in a 5’ to 3’ direction. However, DNA polymerase cannot begin the formation of this new chain on its own and can only add nucleotides to a pre-existing 3'-OH group. A primer is therefore needed, at which nucleotides can be added. Primers are usually composed of RNA and DNA bases and the first two bases are always RNA. These primers are made by another enzyme called primase.
Although the function of DNA polymerase is highly accurate, a mistake is made for about one in every billion base pairs copied. The DNA is therefore “proofread” by DNA polymerase after it has been copied so that misplaced base pairs can be corrected. This preserves the integrity of the original DNA strand that is passed onto the daughter cells.

A surface representation of human DNA polymerase β (Pol β), a central enzyme in the base excision repair (BER) pathway. Image Credit: niehs.nih.gov
Structure of DNA polymerase
The structure of DNA polymerase is highly conserved, meaning their catalytic subunits vary very little from one species to another, irrespective of how their domains are structured. This highly conserved structure usually indicates that the cellular functions they perform are crucial and irreplaceable and therefore require rigid maintenance to ensure their evolutionary advantage.
The researchers will use mice instead of opossums or humans to determine whether the cells of the ear bones originated from the same embryonic cells as the cells that form the jaw in other vertebrates because in this type of experiment, organisms that are ideal are the ones that have a short life span, easy to be researched on and easy to mantain.
It will be very tedious and demanding to use opossums and humans in this type of practical experiment because,it is against the culture and norms guilding human living and existence to use humans as model organisms,opossums as well are very bad model organisms because unlike the mice,opossums are long lived and it will be very difficult to raise and maintain an opossum in a laboratory.
Humans and mice are both mammals just that human is a higher mammal but they share similar features in terms of pattern of development,though there is a clear difference during their early development,so because of the common ancestry shared by the mice and humans,the result of the experiment on the mice with share a close similarity with the pattern that is expected in humans.
