Leptin is released by adipocytes, and I predict that the levels of leptin would be decreased in Nicole when compared to a healthy, female adult of similar age and weight.
The body regulates itself in two ways, neural signals and hormones. Hormones are chemical messengers released by endocrine glands into the blood stream that carry out a particular function in the body. The hormone that regulates appetite and body weight is leptin.
Leptin is released by fat storing cells in the body called adipocytes. The word 'leptin' comes from a Greek word 'leptos' meaning 'fat controller', perfectly fitting its function. Since leptin is stored in the fat tissues, a person's weight has a direct effect on the levels of leptin in a person. When we lose weight, the amount of leptin circulating in the body decreases, leading to more appetite and weight gain.
A lack of leptin in the body, arising from genetic diseases results in uncontrolled appetite and obesity. Generally, female adults also produce less leptin than male adults
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