Some featured visible in an electron microscope may not be present in the living cell because process involved in preparation alter or distort the cell content.
The most effective sort of microscopes can detect even individual atoms; these are called electron microscopes. However, because the materials are destroyed by the electrons, these microscopes cannot be utilized to observe living cells.
Instead of using light to image specimens, electron microscopes use a particle stream of electrons. Images captured with an electron microscope have resolutions between 0.2 and 10 nanometers, which is 10 to 1,000 times better than that of a conventional light microscope. Additionally, samples can be magnified with an electron microscope up to two million times, compared to 2,000 by a light microscope.
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