Secretin is a hormone produced in the intestines that promote the release of insulin from pancreatic islet cells.
Discussion about secretin:
When fatty acids and acidic chyme are present, secretin is released. It performs a number of functions by attaching to secretin receptors, the majority of which are related to digestion and acid neutralization.
In its principal function, secretin tells the pancreas to release bicarbonate ions into the pancreatic juice, raising the pH to between 8 and 8.3 in order to neutralize the acidic chyme. The pancreatic juice's digesting enzymes may function at their best as a result, safeguarding the duodenum's lining.
Additionally, secretin controls the pyloric sphincter's tightness, gastrin release, HCl synthesis, and small intestine motility.
As a result, secretin also encourages the pancreas to produce more insulin in response to ingesting glucose.