Cost effectiveness evaluation can be done by calculating the cost per ml of antacid and also by palatability test.
<h3><u>How to evaluate the cost effectiveness of Antacid ?</u></h3>
Two commercially available antacids are evaluated and compared by:
- determining the number of moles of H⁺ neutralized per gram of each antacid.
- calculating the cost effectiveness of each antacid.
Acid indigestion is a common ailment caused by the overproduction of stomach acid, HCl . Over-the-counter antacids provide some relief from the symptoms of acid indigestion. They are generally made up of some mixture of weak bases such as Mg(OH)₂ , Al(OH)₃ , and CaCO₃ that can react with HCl as shown in these net ionic equations:
H⁺(aq)+OH⁻(aq)⟶H₂O(l)
2H⁺(aq)+CO₂⁻³(aq)⟶H₂O(l)+CO₂(g)
The amount of moles of H⁺ neutralized per gram of antacid will be calculated using the titration technique. In the "back-titration," an excessive amount of HCl will be combined with some antacid. In the presence of the indicator bromophenol blue and the H⁺ that has not yet reacted with the antacid, the H⁺ is subsequently titrated with standardized NaOH to a blue end point.
The amount of OH⁻ required to witness a color shift is considered the end point. The end point is a close approximation of the equivalence point since just the smallest excess of OH⁻ over H⁺ may affect the color of an indicator. (The titration error is the difference between the end point and the equivalence point.) The amount of excess H⁺ that had not been neutralized by the antacid is equal to the amount of OH⁻ that has been added at the equivalency point. One may determine how many moles of H⁺ the antacid has neutralized by knowing the total moles of HCl that have been added.
Total moles of H⁺ = moles of H⁺ neutralized by antacid + moles of H⁺ neutralized by NaOH
It is impossible to determine the individual moles of OH⁻ and CO₂ since both ion species are present in the antacid. Instead, the amount of H⁺ that the antacid neutralized is discovered. One "equivalent" of antacid is referred to as the quantity needed to neutralize one mole of H⁺.
Total equivalent of antacid = Total mole of H⁺neutralized
The antacid with the lowest price per equivalent is the most cost-effective.
To learn more on antacids, refer to:
brainly.com/question/1328376
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