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Dimas [21]
3 years ago
8

Which statement about control of glycogen metabolism is INCORRECT? Which statement about control of glycogen metabolism is INCOR

RECT? Glycogen phosphorylase is activated by phosphorylation. Glucagon signals glycogen breakdown in liver. Epinephrine signals glycogen breakdown in muscle. Glycogen synthase is phosphorylated at only one site.
Biology
1 answer:
GuDViN [60]3 years ago
5 0

Answer:

Glycogen synthase is phosphorylated at only one site.

Explanation:

Glycogen synthase has multiple sites where phosphorylation can occur. Glycogen synthase may have 9 or more sites where it can be phosphorylated as a result of which it's activity is down regulated. It simply means that the regulation of this enzyme does not occur through binary on/off switching, in fact it's activity is modulated over a wide range in response to various signals.

In contrast to glycogen phosphorylase which gets activated when it is phosphorylated at it's serine residues, glycogen synthase gets inactivated by phosphorylation.

As soon as another enzyme GSK3β phosphorylates glycogen synthase, it gets inactivated as a result of which glycogen synthesis halts in the liver.

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3.Metabolic component : third line of defense is slow, best measured by the base excess,eand mostly depends on the renal system which can add or remove bicarbonate ions to or from the ECF.Bicarbonate ions are derived from metabolic carbon dioxide which is enzymatically converted to carbonic acid in the renal tubular cells.There, carbonic acid spontaneously dissociates into hydrogen ions and bicarbonate ions.When the pH in the ECF falls, hydrogen ions are excreted into urine, while bicarbonate ions are secreted into blood plasma, causing the plasma pH to rise.The converse happens if the pH in the ECF tends to rise: bicarbonate ions are then excreted into the urine and hydrogen ions into the blood plasma.




Buffers usually consist of a weak acid and its conjugate base; this enables them to readily absorb excess H+ or OH–, keeping the system’s pH within a narrow range.

Maintaining a constant blood pH is critical to a person’s well-being. The buffer that maintains the pH of human blood involves carbonic acid (H2CO3), bicarbonate ion (HCO3–), and carbon dioxide (CO2). When bicarbonate ions combine with free hydrogen ions and become carbonic acid, hydrogen ions are removed, moderating pH changes. Similarly, excess carbonic acid can be converted into carbon dioxide gas and exhaled through the lungs; this prevents too many free hydrogen ions from building up in the blood and dangerously reducing its pH; likewise, if too much OH– is introduced into the system, carbonic acid will combine with it to create bicarbonate, lowering the pH.
Example: Antacids, which combat excess stomach acid, are another example of buffers.


ECF =Extra cellular fluid




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