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wlad13 [49]
3 years ago
9

"No one questions the use of the auto for transporting groceries, getting to one’s place of work or to the golf course, or in pl

ace of the porch for "cooling off after supper" on a hot summer evening; however much the activities concerned with getting a living may be altered by t the fact that a factory can draw from workmen within a radius of forty-five miles…these things are hardly major issues. But when auto riding tends to replace the traditional call in the evening parlor as a way of approach between the unmarried, "the home is endangered," and all-day Sunday motor trips are a "threat against the church"; it is in the activities concerned with the home and religion that the automobile occasions the greatest emotional conflicts…"
Robert S. and Helen Merrell Lynd, The Automobile and Family Life (1929)

1. What concern(s) did many people have about the increased use of the automobile?
2. What was the automobile challenging?
Business
1 answer:
olga55 [171]3 years ago
5 0

Answer:

1. The usage of automobiles, individuals within the early twentieth century were involved that it terminate the values and norms that the Americans had at that point. A number of their considerations were that currently vehicle riding might substitute ancient calls to the sunset parlor among widowed men and girls and so the development of outdated relations and therefore the old-style plan of a family would be vulnerable. Individuals conjointly dreaded that families would substitute their weekly appointment to the religious on Sunday with daytime long visits in cars.

2. Challenges that automobiles were faced are the traditional activities involved with the family house and faith. They were same to supply a good deal of responsive conflict.

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How can I start for drug design to end up having a career as a drug designer?
MatroZZZ [7]

Answer:

Inorder to start for drug design to end up having a career as a drug designer, one needs to follow the processes below;

1. Discovery

2. Product characterization

3. Formulation, delivery, packaging development

4. Phamacokinetics and drug disposition

5. Preclinical toxicology testing and IND application

6. Bioanalytical testing

7. Clinical trials

Explanation:

Drug design is a method in which one develops new medicinal drugs based on the knowledge of a biological target.

The knowledge of the biological target is it's molecular make up. Once the molecular information about the target has been determined, the drug is developed to compliment the bio-molecular properties of the target.

The bio-molecular properties usually considered are the shape and the charge.

There are seven major processes to complete drug design. They are as follows;

<em>1. Discovery</em>

This starts with a target identification where the biochemical relationship involved in the disease condition. The interaction between a drug candidate and the drug target is determined using rigorous screening processes. A lead compound is chosen after effective review.

<em>2. Product characterization</em>

The candidate molecule is then classified and its characteristics noted.

<em>3. Formulation, delivery, packaging development</em>

Formulations for proper drug delivery parameters should be determined. This will include all parameters of shipment and storage to ensure proper and safe delivery.

<em>4. Phamacokinetics and drug disposition</em>

Pharmacokinetics(Pk) offer useful feedback to the formulation scientists. Pk offers parameters such as area under the curve and the maximum concentration of the drug in the blood and the time at which the maximum concentration is reached.

<em>5. Preclinical toxicology testing and IND application</em>

This involves the testing of the bio-activity, safety and efficacy of the formulated drug product

<em>6. Bioanalytical testing</em>

This is important for proper characterization of the molecule

<em>7. Clinical trials</em>

The clinical trial are conducted by grouping them into three types, majorly;

human pharmacology, therapeutic exploratory, and therapeutic confirmatory

6 0
4 years ago
What early invention improved the transcontinental transportation of people and goods?
charle [14.2K]
The steam locomotive
8 0
3 years ago
Even though most corporate bonds in the United States make coupon payments semiannually, bonds issued elsewhere often have annua
Bingel [31]

Answer:

Current price of the bond $928.95  

Explanation:

Th price of the bond is the same as the present value of the bond today which is given by the below excel formula:

=pv(rate,nper,pmt,fv)

rate is the yield to maturity on the bond of 8.6%

nper is the tenor of the bond which is 25 years

pmt is the coupon interest payable annually by the bond which is 7.9%*1000=79

fv is the future value repayable on redemption which is 1000 euros

=pv(8.6%,25,79,-1000)

pv=$928.95  

The current price of the bond is $928.95   as computed using the present value formula in excel

3 0
3 years ago
Charlie, the CEO of Collier Chemical, likes to boast that his company offers the highest salaries in the industry, has excellent
lidiya [134]

Answer: hygiene factors

Explanation:

From the analysis in the question, we can infer that the organization is focusing on the hygiene factors. According to Herzberg, even though the hygiene factors are vital, they don't motivate workers but they may lead to dissatisfaction at workplace when they're not in place.

Examples of hygiene factors are the organizational policies, relationships with co-workers, compensation, physical work environment, and job security.

5 0
4 years ago
The American economy consists of a complex combination of organizations and variables, such as countless companies differing in
Jlenok [28]

Answer:

The correct answer is The Theory of complexity.

Explanation:

The Theory of Complexity and Organizations, also called complexity strategy or adaptive complex organization, is the use of complexity theory in the field of strategic management and organizational studies.

The complexity theory has been used in the fields of strategic management and organizational studies. Areas of application include an understanding of how organizations or companies adapt to their environment and how they deal with situations of uncertainty. The theory treats organizations and companies as collections of strategies and structures. The structure is complex, because they are dynamic networks of interactions, and their relationships are not the result of the aggregation of individual static entities. They are adaptive; Because individual and collective behaviors mutate and organize themselves in response to the initial changes of micro events or the total set of events.

7 0
3 years ago
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