Answer:
Option (2) and (3).
Explanation:
Cancer is the uncontrolled division of the cell that might results in the loss of apoptosis in the cells. The cancer cell shows the property like angiogenesis and loss of contact inhibition.
Both the hereditary factors like mutations in some gene and environmental factors like any mutagen may inhibit the process of the cell division. Both these factors mainly inhibits the gene that are responsible for the regulation of the cell cycle like p53, Rb.
Thus, the correct answer is option (2) and (3).
