Answer:
4, 2, 1, 3
4. Mesenchymal cells aggregate.
2. Osteoblasts differentiate within mesenchymal connective tissue.
1. Clusters of osteoblasts form osteoid that becomes mineralized.
3. Spicules of bone radiate out from the ossification centers.
Explanation:
Intramembranous Ossification is the process whereby the bones are developed from fibrous membrane.
It is one of the most essential process in the development of a foetus.
It starts during the sixth to the seventh week in the life of a foetus and it continues up till the adolescent stage in the life of a child.
Intramembranous ossification involves the development of the flat bones of the skull, the mandible, and the clavicles.
Firstly, the cells of the mesenchymal cells aggregate and come together.
The osteoblasts differentiate within mesenchymal connective tissue. The clusters of osteoblasts that form osteoid and become mineralized and spicules of bone radiate out from the ossification centers.
