Suppose a geneticist mutates the gene for the poly(A) tail-binding protein (PABP) in an eukaryotic cell line. The resulting muta
nt protein cannot bind to poly(A) tails. What is the effect of the PABP mutation in the cultured cells?A-Transcription will not occur in the cultured cells, because PABP is an essential transcription factor.B-Translation will not occur in the cultured cells, because mRNAs will be degraded at a greater rate than normal.C-Transcription will occur in the cultured cells, but the resulting transcript will be longer than normal.D-Translation will occur in the cultured cells, but the resulting polypeptide will be longer than normal.E-Replication will not occur in the cultured cells, because PABP determines the location of the origin of replication.
The answer is: B-Translation will not occur in the cultured cells, because mRNAs will be degraded at a greater rate than normal
Explanation:
The translation process will not happen in cells that are altered, because messenger RNA (mRNA) breaks down at a much higher rate than normal. In such a way that the PABP protein would bind to the poly A tail of the messenger RNA and this is essential in the stability of the messenger RNA.
Translation will not occur in the cultured cells, because mRNA will be degraded at a greater rate than normal.
The reason of degradation is that scientist mutated the gene in eukaryotic cell which means translation will only occur in eukaryotic cell not in cultured cell.
