Water makes up 60% of a human body, and can be loss due to peeing, sweating, etc. In fact, the human generally loses so much water that the average human is suggested to drink 15 cups of water a day, depending of course on job, amount of exercise, body build, etc.
The integumentary system is the system that protects the body from damage such as loss of water or abrasion from outside. For example, nails, hair, skin, etc.