Where does first pass metabolism occur? / what route of administration is used to avoid complete first pass metabolism?

1 answer:

7 0

First pass metabolism of a drug is said to occur when the concentration of a drug that is administered orally is significantly reduced before it reaches the systemic circulation.
First pass metabolism usually occur in the liver.
The routes of drug administration that avoid complete first pass metabolism are: sublingual, transdermal, rectal and inhalation.

You might be interested in

Where is the DNA located in a eukaryotic cell?

PtichkaEL [24]

The cytoplasm I hope I helepd

8 0

3 years ago

You are researching a public essay on growing Internet censorship. Which of these sources is the most relevant and credible?

ANEK [815]

"A <span>recent survey by a news agency showing that most parents across the country favor Internet censorship" is the one source among the following that is the </span><span>most relevant and credible. The correct option among all the options that are given in the question is the third option or option "C". I hope it helps you.</span>

5 0

4 years ago

Pepsin, a digestive enzyme that degrades proteins in the stomach, is synthesized as pepsinogen and converted to active pepsin in

kipiarov [429]

Digestive enzymes help to break down food in its simplest form. Pepsin is a digestive enzyme which leads to the degradation of proteins in the stomach. It is produced as pepsinogen and converted to active pepsin in the stomach by the removal of several amino acids.

<h3>What is pepsin?</h3>

Pepsin is a digestive enzyme which is present mainly in the gastric juice in stomach and helps to breakdown protein into peptides.

This pepsin is present in the stomach in the form of inactive pepsinogen. This pepsinogen gets active in the stomach by the action of hydrochloric acid.

Pepsinogen gets active and forms pepsin.

Thus, it can be concluded that the digestive enzyme pepsin degrades protein in stomach and is synthesized as pepsinogen and gets converted into active pepsin in stomach by removal of several amino acids.

For more details regarding digestive enzymes, visit:

brainly.com/question/24145559

#SPJ4

5 0

2 years ago

Examples of the three principles of sustainable include:

musickatia [10]

Answer:A. Solar energy, which enables plants to photosynthesize and helps humans produce electricity

Explanation:

8 0

3 years ago

The movement of water molecules through the environment is known as the

nevsk [136]

Answer:

osmosis

Explanation:

Movement of a solvent (such as water) through a semipermeable membrane (as of a living cell) into a solution of higher solute concentration that tends to equalize the concentrations of solute on the two sides of the membrane.

6 0

3 years ago