secreted by the gonadotropic cells of the anterior pituitary gland, and regulates the development, growth, pubertal maturation, and reproductive processes of the body
Answer:
DNA ligase
Explanation:
DNA replication is a process whereby a particular DNA makes a copy of or synthesizes itself. It consists of several steps with some important enzymes for successful, error free replication. The various steps are as follows;
- Unwinding of the double helix structure of the DNA and formation of replication fork. The enzyme involved here is the DNA helicase.
- Primer, a short piece of RNA becomes synthesized and binds to the 3' end of one of the 2 strands of the DNA, the leading strand. The enzyme involved is the DNA primase.
- Replication of the <em>leading strand</em> then proceeds with the elongation of the primer through the addition of bases in the 5' to 3' direction leading to the formation of continuous strands.
- The other strand of the DNA, known as the <em>lagging strand </em>starts its own replication by binding with multiple primers at different regions of the strand. Bases are then added to each primer leading to the formation of several, short discontinuous DNA strands known as Okazaki fragments. The enzyme involved in the elongation process is the DNA polymerase.
- Next is the termination of the replication process after the formation of the continuous and discontinuous strands. Exonuclease enzyme removes primers from the synthesized strands. Primers are replaced by appropriate DNA bases and the Okazaki fragments are joined to form a unified DNA strand by an enzyme known as the DNA ligase.
The many, few nucleotides long DNA segments observed by the Biochemist are the Okazaki fragments that should have been joined together by the DNA ligase.
Hence, DNA ligase must have been the component left of the mixture.
Answer:
<u><em>They take nutrients needed by healthy cells, and as they grow they interfere with the function of normal cells and organs.</em></u>
Explanation:
Many mutations can lead to the formation of cancer. Cancer can be described as an abnormal type of cell division of the cells of the body. As cancer cells are the cells of the body dividing abnormally, the immune cells fail to fight them. These cells keep on dividing and also disturb the functioning of the neighbouring cells and tissues. They even take up most of the nutrients required by normal body cells hence, being very toxic for the normal cells.
Answer:
In eukaryotic cells you find core and proximal promoters.
Promotors are specific DNA sequences where transcription factors (proteins) and RNA polymerase binds to initiate transcription. Promotors are located upstream the coding sequence
Core promoters are where RNA polymersae binds and proximal promoters are where transcription factors bind.
Enhancer elements are DNA sequences where transcription factors (proteins) bind to increase the rate of expresion of an specific gene. Enhancers can be located either upstream, downstream or thousands of nucleotids away from the of the coding region.
Explanation:
Promoters and enhancer are key elements for controling gene regulation. Transcription begins when chromatin rearranges from a condensed state to a accesible state, this allow to transcrition factors and RNA polymerase to bind specif DNA sequences (promotors). Proteins bind to enhancers , this complex develops a DNA loop, so that the protein that is bound to the enhancer interacts with the RNA polymersase. When this interaction is made, the activity of the RNA polymerase is increased.
