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Alex777 [14]
3 years ago
11

Cholesterol has a much higher profile than the other lipids because of its association with heart disease. Despite its lethal re

putation with the public, cholesterol is vital to the body: it maintains proper fluidity of animal cell membranes and is the precursor of steroid hormones such as progesterone, testosterone, estradiol, and cortisol. Cholesterol is synthesized in the liver and, to a lesser extent, in other tissues. The rate of its synthesis is highly responsive to the cellular level of cholesterol. Cholesterol synthesis can be effectively blocked by a class of compounds called statins. The market of the statins is estimated at $20 billions.
Explain the mechanism of action of statins.
Biology
1 answer:
yaroslaw [1]3 years ago
5 0

Answer and Explanation:

The mechanism of action of statins begins with the inhibition of a protein called HMG-CoA reductase, allowing its substrate to accumulate in the body and promote cholesterol reduction. At that moment, a transporter called OATP (Organic Anion Transporting Polypeptides) takes statins to the epatic tissue where they will be transformed and metabolized until they are eliminated through bile. This elimination is influenced by the P-glycoprotein, which is the main cause of the efflix presented by the bili. This process can get help from other molecules like some protease inhibitors, digoxin and cyclosporine.

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Why are scientific theories often so powerful?
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If a corn plant was heterozygous for kernel color and seed shape, what would be the genotype of the plant?
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<em>The genotype of the plant will be PpSs and the phenotype will be purple colour and smooth shaped. </em>

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Considering the description in the question, we know that purple colour is dominant over the yellow colour and smooth shape is dominant over the wrinkled shape.

A homozygous trait can be described as a trait which arises due to the same alleles of a gene. A heterozygous trait arises when both the alleles of a gene are different. In such a case, one allele will be dominant over the other one and the phenotype of the dominant allele will be seen in the plant. As purple colour and smooth shape are dominant traits, hence they will be seen in the heterozygous plant.

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