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Alex777 [14]
3 years ago
11

Cholesterol has a much higher profile than the other lipids because of its association with heart disease. Despite its lethal re

putation with the public, cholesterol is vital to the body: it maintains proper fluidity of animal cell membranes and is the precursor of steroid hormones such as progesterone, testosterone, estradiol, and cortisol. Cholesterol is synthesized in the liver and, to a lesser extent, in other tissues. The rate of its synthesis is highly responsive to the cellular level of cholesterol. Cholesterol synthesis can be effectively blocked by a class of compounds called statins. The market of the statins is estimated at $20 billions.
Explain the mechanism of action of statins.
Biology
1 answer:
yaroslaw [1]3 years ago
5 0

Answer and Explanation:

The mechanism of action of statins begins with the inhibition of a protein called HMG-CoA reductase, allowing its substrate to accumulate in the body and promote cholesterol reduction. At that moment, a transporter called OATP (Organic Anion Transporting Polypeptides) takes statins to the epatic tissue where they will be transformed and metabolized until they are eliminated through bile. This elimination is influenced by the P-glycoprotein, which is the main cause of the efflix presented by the bili. This process can get help from other molecules like some protease inhibitors, digoxin and cyclosporine.

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In which stage do vertebrate embryos or offspring show the most similarities?
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Explanation:

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Black-bellied seedcrackers have either small beaks (better for eating soft seeds) or large beaks (better for hard seeds). There
uysha [10]
<h2>Disruptive Selection.</h2>

Explanation:

  • Disruptive selection is also known as Diversifying selection.
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3 years ago
What happens when a person who is allergic to ragweed encounters ragweed?
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Ragweed antigens bind ragweed and then bind mast cells which release histamine 

<span>Allergies develop because of a Th2 response against the allergen. </span>

5 0
3 years ago
Correctly match the following: - fibrous joint between radius and ulna - fibrous joint that unites bones of the skull - articula
topjm [15]

Answer:

- fibrous joint between radius and ulna: C. syndesmosis

- fibrous joint that unites bones of the skull: H. suture

- articulation between teeth and bone: J. gomphosis

- joint with a cavity between bones: E. synovial

- the epiphyseal plate: F. synchondrosis

- articulation between two pubic bones: A. symphysis

- permits opposition and reposition:  B. saddle  

- fibrocartilagenous fluid filled sacs outside the joint cavity: G. meniscus

- most common degenerative joint disease: D. osteoarthritis    

- movement of the sole laterally:  I. eversion  

Explanation:

The syndesmosis can be defined as a fibrous joint held together by ligaments. Sutures are fibrous joints of tissue that link the cranial bones of the skull. A gomphosis is a mobile fibrous that binds the teeth into sockets in the mandible and maxilla. Synovial joints are joints found between bones that move against each other (e.g., shoulder bones). They (synovial joints) are the most common class of joints found in the body. A symphysis is a cartilaginous, slightly movable, joint between two bones. A saddle is a synovial joint whose opposing surfaces are concave and convex, respectively. Osteoarthritis is the most common type of arthritis, this condition occurs when the protective cartilage surrounding the bones wears away over time. Finally, eversion refers to a type of movement of the foot which occurs in the auctioneering joint.

8 0
3 years ago
Explain how the availability of resources in the environment is linked to exponential growth of a species
Alinara [238K]

Answer: Exponential growth occurs when resources in the environment are abundantly available to a species.

Explanation: When a food source amount drops, so does the survival rate of the predator that eats that specific food source. When a food source grows too abundantly at too fast a rate, predators increase in numbers.

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3 years ago
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