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tino4ka555 [31]
3 years ago
11

What are ejcs? Describe the importance of the ejc complexes for the export and stability of mrnas.

Biology
1 answer:
Alex Ar [27]3 years ago
5 0

Explanation:

The Exon Junction Complex (EJC) is a eukaryotic molecular machine that interacts with spliced mRNA upstream of exon-exon junctions, providing a binding platform for other trans-acting proteins that determine the fate of the mRNA.  The spliceosome deposits the ~335kD EJC in a non-sequence specific manner 20-24 nucleotides upstream of an exon-junction.  Functionally, the EJC aids in nuclear export of spliced mRNAs, assists in nonsense-mediated decay of incorrectly spliced mRNAs containing premature stop codons, and enhances translation efficiency.

Pre-mRNA bound by a spliceosome is usually not exported from the nucleus, so as to make sure that only fully-processed mRNA travels to the cytoplasm to be translated.  A protein called the mRNP exporter binds to the EJC, both through RNA interactions and interactions with the EJC-associated protein REF (RNA export factor) to help pre-mRNA exit the nuclear pore complex.

Interestingly, the efficiency of unspliced mRNA export is dependent on the length; longer mRNAs are exported more efficiently than shorter mRNAs. In spliced mRNAs, however, once the 5' exon is long enough to bind the EJC, the length of the spliced mRNA does not affect the export efficiency.

There are a certain number of EJCs in a cell, and they must be recycled in order to continue tagging mature mRNAs. Once in the cytoplasm, the ribosome-associated regulator protein (PYM) acts as a dissociation factor.

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Oliga [24]
Where are the answers?? Lol
3 0
3 years ago
A woman who is a carrier for hemophilia marries a hemophiliac man. What will be their children’s possible phenotypes?
Morgarella [4.7K]

Answer:

Hemophilia is a sex-linked recessive disorder in which a person's blood do not clots and he can bleed to death even after minor injuries because blood will keep running due to a small cut.

It is a recessive trait which means that even if one normal gene is present along with Hemophiliac gene, the person will not have the disease and he will be the carrier.

Question: What will be their children’s possible phenotypes?

If a woman who is a carrier for hemophilia marries a hemophiliac man, their genotypes can be denotes as :

Here H, indicate normal gene and small h indicate defected (hemophilia) gene.

Parents:                      XHXh                   X           XhY

Offspring:                   XHXh : XHY:  XhXh:  XhY

Phenotype of offspring:

XHXh:  The child will be daughter and normal (25 % chances)

XHY:     The child will be son and normal (25 % chances)

XhXh:   The child will be girl and Hemophiliac (25 % chances)

XhY:      The child will be son and Hemophiliac (25 % chances)

Hope it helps!

5 0
3 years ago
Some animals hibernate during winter. What molecules provides energy to them during the time .
Vera_Pavlovna [14]

Answer:

Fat

Explanation:

Animals rely on fat for energy during hibernation.

8 0
3 years ago
Most red deer who successfully reproduce have about four fawns during their lifetimes. However, a small percentage of red deer p
Rasek [7]

Answer:

Natural selection will favor red deer that produce a dozen or more offspring that survive for at least a year.

Explanation:

Natural selection results in adaptation, which means the increase of the aptitude phenotype.  Aptitude is the contribution of each genotype to the next generation.

Natural selection is the result between the individual phenotype and the environment that determines the destiny of genes. It is the differential capability of individuals to leave offspring.

Aptitude (or fitness) is the phenotype that results in the survival, fertility, and capability of having a mate. It is a way of measuring the individual ability to leave fertile offspring. Aptitude must be significant to the natural selection act in its favor.  

Natural selection, eventually, will favor red deer that produce a dozen or more offspring that survive for at least a year. These animals have more chances of leaving fertile descendants that will be able to grow, develop, survive, and reproduce. They have a higher aptitude than those individuals that only have four fawns during their lifetimes. These animals have fewer probabilities of leaving survival descendants able to reproduce.

3 0
3 years ago
What is secreted by the gastric mucous neck cells and pancreatic duct cells to neutralize stomach acid?
erik [133]

Answer:

Bio carbonate ions

Explanation:

The pancreas secrets an aqueous mixture ( water, digestive enzymes and bicarbonate ions) during digestion of food substances from the stomach into the duodenum to begin the process of absorption and assimilation.

The pancreatic duct are lined with duct cells. These are cells which secretes HCO3- ,into the aqueous mixture. This ion is basic. Therefore it  neutralizes the acidity of the  of  the chyme to  released from the stomach to enable the pancreatic enzyme to work.

The bicarbonate ions also prevent the walls of the pancreases from getting burnt by the effect if the acidity of the chyme.

3 0
3 years ago
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