Question

In bacteria, the antibiotic erythromycin prevents ribosomes from functioning. The MOST likely reason that bacteria die from treatment with erythromycin is because the antibiotic____________

Answer 1

Answer:

inhibits translation

Explanation:

Bacteriostatic macrolide antibiotic produced by Streptomyces erythreus. Erythromycin A is considered its main active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process that inhibits peptidyl transferase activity and interferes with the translocation of amino acids during translation and protein assembly.

The bacteriostatic effect consists in producing the inhibition of bacterial growth; Meanwhile, immunogenesis is expected to provide the necessary defensive elements for disease control. Therefore, these antimicrobials should not be indicated to the immunocompromised patient. They act in the stationary phase of bacterial growth.

Some antibiotics have a bactericidal or bacteriostatic effect depending on whether the drug acts in vivo or in vitro, and depending on the dose administered. For example, Amphotericin B, has fungistatic effect in vivo and fungicide in vitro; Streptomycin and erythromycin have bactericidal effect when administered at high doses and bacteriostatic effect if administered at low doses.